A 19th-century pioneer family leaves Ohio and moves west to Kansas, encountering danger and hostility, during which the widowed father of one family falls in love with another pioneer whose father has been murdered by vigilantes.
An American arms dealer, Wilson, journeys south of the border during the Mexican Revolution and immediately sparks trouble when he provokes federal troops. His actions impress the revolutionaries, whom he joins forces with, and Wilson convinces his new allies to go after a rival arms dealer named Kennedy. When Wilson falls for Kennedy’s wife, Lisa and the revolutionaries eventually turn on him, the gunrunner finds himself in the line of fire.
A young frontier couple elope, are chased by the girl’s father and brothers, join up with an escaped convict and get mixed up with a charlatan preacher.
Old West highwayman Bill Miner, known to Pinkertons as “The Gentleman Bandit,” is released in 1901 after 33 years in prison, a genial and charming old man. He goes to Washington to live and work with his sister’s family. But the world has changed much while he has been away, and he just can’t adjust. So he goes to Canada and returns to the only thing familiar to him — robbery (with stagecoaches changed to trains).
In one of his rare movie starring assignments, William Talman plays a dual role in The Persuader. Talman is seen as gunslinger Matt Bonham and his twin brother, preacher Mark Bonham. When Mark is killed by outlaw leader Bick Justin, Matt takes his brother’s place in the pulpit, ramming the Fear of God down the throats of the wanton townspeople. Impressed by Bonham’s courage, the townsfolk begin to follow the straight and narrow path.
A former gunfighter who went to prison but then took up religion arrives in a western town as the new preacher. There he finds a feud between the ranchers and the farmers. The Railroad Agent is after the ranchers land and has his men causing all the trouble. The new preacher sets out to bring the two sides together and he says he will not need a gun.
Vane hires Candel to haul his locomotive by freight wagon to Omaha. Ross knows that the railroad will mean the end of his freighting business and plans to make sure the locomotive does not get through. When his attempts are foiled, he and his men take all the guns and leave. With the Indians about to attack, Candel and his crew find themselves defenseless.
The story involves an overland journey through hostile Cheyenne territory to rescue two white women captured by the Cheyenne. One has turned renegade and is not anxious to be rescued as she is about to be married to Chief Thunder Hawk.